Madrigal Pharmaceuticals, Inc.

MDGL US5588681057

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Capitalization
Mid-cap

Madrigal Pharmaceuticals Inc is a clinical-stage biopharmaceutical company. It focuses on the development and commercialization of therapeutic candidates for the treatment of cardiovascular-metabolic diseases and non-alcoholic steatohepatitis (NASH). The product portfolio of the company includes MGL-3196, an orally administered, small-molecule liver-directed B-selective THR agonist, which is used for the treatment of non-alcoholic steatohepatitis and familial hypercholesterolemia. Also, MGL-3196 reduces triglycerides in the plasma and liver by increasing fat metabolism and shows an anti-diabetic action.

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Website
Annual Performance 1
2021 2022 2023 2024 2025
-23% 222% -19% 36% 2%
Annual Insiders Turnover, USD 2

1 annual and historical performance metrics are recalculated on a daily basis;
2 represents the total value of insider transactions (both buying and selling);

Insider Activity
📊
Transactions
268
🙍
Insiders
12
Person Price Shares Total Published Completed
Sibold William John
CEO 		445.63
USD 		7,279
Sold 		3,243,741
USD 		09/09/2025 09/09/2025
Sibold William John
CEO 		401.00
USD 		1,131
Sold 		453,531
USD 		21/08/2025 21/08/2025
Sibold William John
CEO 		400.03
USD 		6,485
Sold 		2,594,225
USD 		21/08/2025 21/08/2025
Kelley Shannon T
SR OFF 		375.75
USD 		190
Sold 		71,393
USD 		18/08/2025 18/08/2025
Kelley Shannon T
SR OFF 		372.44
USD 		252
Sold 		93,855
USD 		18/08/2025 18/08/2025
Kelley Shannon T
SR OFF 		370.06
USD 		84
Sold 		31,085
USD 		18/08/2025 18/08/2025
Kelley Shannon T
SR OFF 		376.62
USD 		42
Sold 		15,818
USD 		18/08/2025 18/08/2025
Kelley Shannon T
SR OFF 		369.64
USD 		126
Sold 		46,575
USD 		18/08/2025 18/08/2025
Kelley Shannon T
SR OFF 		358.66
USD 		458
Sold 		164,266
USD 		18/08/2025 18/08/2025
Kelley Shannon T
SR OFF 		371.35
USD 		84
Sold 		31,193
USD 		18/08/2025 18/08/2025

Integrated EOD Stock Data and Insider Transactions Chart

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Historical Performance
1M 3M 6M 1Y 3Y 5Y All Time
57% 16% 20% 35% 209% 1759% 2668%
Last 52W Low 52W High All-Time Low All-Time High β
436.28 267.56 458.66 267.56 458.66
Company Insiders
Person / Entity Transactions Turnover, USD Average, USD First Last
Friedman Paul A 66 99,597,718.79 1,509,056.35 03/04/2024 13/08/2025
Taub Rebecca 50 48,553,743.89 971,074.88 03/04/2024 12/08/2025
Bate Kenneth 32 18,995,765.69 593,617.68 01/04/2024 15/08/2025
Daly James M 19 13,593,755.86 715,460.83 01/04/2024 27/02/2025
Craves Fred B 27 12,196,033.40 451,704.94 14/05/2024 13/03/2025
Waltermire Robert E. 25 8,858,836.84 354,353.47 12/12/2023 05/03/2025
Sibold William John 5 8,374,007.59 1,674,801.52 09/09/2024 09/09/2025
Levy Richard S 11 6,087,038.01 553,367.09 01/04/2024 07/11/2024
Lynch Brian Joseph 8 2,031,774.00 253,971.75 29/11/2023 05/12/2023
Huntsman Carole 12 996,938.92 83,078.24 21/11/2024 03/03/2025
Dier Mardi 3 720,592.38 240,197.46 03/03/2025 10/03/2025
Kelley Shannon T 10 694,386.42 69,438.64 17/01/2025 18/08/2025

Insiders marked in yellow represent long-term insiders. These are individuals who have engaged in transactions for over 3 years and have conducted at least 10 transactions or reached a cumulative turnover of $1M USD. When examining transaction clusters, we prioritize those conducted by long-term insiders for analysis.

Connected Companies 3
Name ISIN Ticker
PROTARA THERAPEUTICS, INC. US74365U1079 TARA

3 the firms where the current insiders have executed transactions.

Stock Advanced Metrics
Delta Correlation subscribe 🔒
Upper Bound of Standardized Transaction Amount (ubsta), USD 4 subscribe 🔒

4 represents the maximum expected transaction amount for a company's insiders, calculated based on historical data. It provides insight into the typical range of insider transaction amounts and helps in identifying unusually large transactions.

5 a proprietary metric reflecting the consistency of insider trading behavior within a company. A higher discipline index suggests more regular and predictable insider transactions.