Leap Therapeutics, Inc.

LPTX US52187K2006

💰
Capitalization
Small-cap

Leap Therapeutics Inc is a biopharmaceutical company developing novel biomarker-targeted antibody therapies designed to treat patients with cancer by inhibiting fundamental tumor-promoting pathways, targeting cancer-specific cell surface molecules, and harnessing the immune system to attack cancer cells. The company's key clinical-stage drug candidate is sirexatamab (DKN-01), which targets Dickkopf-related protein 1 (DKK1) and is being studied in a clinical trial in patients with colorectal cancer. In addition, it also has a preclinical program to develop a proprietary monoclonal antibody, called FL-501 which works by inhibiting the GDF-15 protein.

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Website
https://www.leaptx.com
Annual Insiders Turnover, USD 2

1 annual and historical performance metrics are recalculated on a daily basis;
2 represents the total value of insider transactions (both buying and selling);

Insider Activity
📊
Transactions
4
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Insiders
3
Person Price Shares Total Published Completed
Cavanaugh James H
 3.14
USD 		261,840
Sold 		822,178
USD 		17/11/2025 17/11/2025
Mirabelli Christopher
 3.14
USD 		261,840
Sold 		822,178
USD 		17/11/2025 17/11/2025
Cavanaugh James H
 3.14
USD 		261,840
Sold 		822,178
USD 		17/11/2025 17/11/2025
Mirabelli Christopher
 3.14
USD 		414,479
Sold 		1,301,464
USD 		17/11/2025 17/11/2025
Integrated EOD Stock Data and Insider Transactions Chart

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The visibility of insider buy and sell transactions on this chart should not be the sole factor in your decision to buy or sell a particular stock. Always consider the following dynamic reports for a broader understanding of stock market activities:

 

Last
52W Low
52W High
All-Time Low
All-Time High
Company Insiders
Name Stats Turnover Average First Last
Mirabelli Christopher
2 transactions
Buy 0% Sell 100%
2.12M 1.06M 17/11/2025 17/11/2025
Onsi Douglas E
2 transactions
Buy 0% Sell 100%
2.12M 1.06M 17/11/2025 17/11/2025
Cavanaugh James H
2 transactions
Buy 0% Sell 100%
1.64M 822.18K 17/11/2025 17/11/2025

Insiders marked in yellow represent long-term insiders. These are individuals who have engaged in transactions for over 3 years and have conducted at least 10 transactions or reached a cumulative turnover of $1M USD. When examining transaction clusters, we prioritize those conducted by long-term insiders for analysis.

Stock Advanced Metrics
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Upper Bound of Standardized Transaction Amount (ubsta), USD 4 subscribe 🔒

4 represents the maximum expected transaction amount for a company's insiders, calculated based on historical data. It provides insight into the typical range of insider transaction amounts and helps in identifying unusually large transactions.

5 a proprietary metric reflecting the consistency of insider trading behavior within a company. A higher discipline index suggests more regular and predictable insider transactions.