Insmed Incorporated

INSM US4576693075

Insmed Inc is a global biopharmaceutical company transforming the lives of patients with serious and rare diseases. The company's first commercial product is ARIKAYCE (amikacin liposome inhalation suspension), approved in the US for the treatment of Mycobacterium Avium Complex (MAC) lung disease as part of a combination antibacterial drug regimen for adult patients with limited or no alternative treatment options. The company's earlier-stage clinical pipeline includes Brensocatib, a novel oral reversible inhibitor of dipeptidyl peptidase 1 with therapeutic potential in non-cystic fibrosis bronchiectasis and other inflammatory diseases; and INS1009, an inhaled formulation of a treprostinil prodrug that may offer a differentiated product profile for pulmonary arterial hypertension.

Annual Performance ¹

2021	2022	2023	2024	2025
-18%	-29%	62%	131%	-0%

Annual Insiders Turnover, USD ²

¹ annual and historical performance metrics are recalculated on a daily basis;
² represents the total value of insider transactions (both buying and selling);

Insider Activity

Person	Price	Shares	Total	Published	Completed
Schaeffer Orlov S Nicole SR OFF	144.60 USD	32,091 Sold	4,640,359 USD	12/09/2025	12/09/2025
Schaeffer Orlov S Nicole SR OFF	146.57 USD	7,304 Sold	1,070,547 USD	12/09/2025	12/09/2025
Sharoky Melvin Md	145.39 USD	10,000 Sold	1,453,900 USD	11/09/2025	12/09/2025
Schaeffer Orlov S Nicole SR OFF	144.60 USD	32,091 Sold	4,640,359 USD	12/09/2025	12/09/2025
Schaeffer Orlov S Nicole SR OFF	147.46 USD	6,158 Sold	908,059 USD	12/09/2025	12/09/2025
Schaeffer Orlov S Nicole SR OFF	146.57 USD	7,304 Sold	1,070,547 USD	12/09/2025	12/09/2025
Sharoky Melvin Md	145.39 USD	10,000 Sold	1,453,900 USD	11/09/2025	12/09/2025
Schaeffer Orlov S Nicole SR OFF	145.67 USD	30,967 Sold	4,510,963 USD	12/09/2025	12/09/2025
Schaeffer Orlov S Nicole SR OFF	147.46 USD	6,158 Sold	908,059 USD	12/09/2025	12/09/2025
Schaeffer Orlov S Nicole SR OFF	145.67 USD	30,967 Sold	4,510,963 USD	12/09/2025	12/09/2025

Load More

Integrated EOD Stock Data and Insider Transactions Chart

Sign in or subscribe to include Insmed Incorporated to your watchlist and receive automatic alerts for upcoming transactions.

Generate

The visibility of insider buy and sell transactions on this chart should not be the sole factor in your decision to buy or sell a particular stock. Always consider the following dynamic reports for a broader understanding of stock market activities:

• Insider Transaction Amount Distribution
• Insider Trading Seasonality
• Delta Correlation Analysis

 

Historical Performance

1M	3M	6M	1Y	3Y	5Y	All Time
-2%	-7%	164%	247%	157%	128%	305%

Last	52W Low	52W High	All-Time Low	All-Time High	β
162.32	64.81	162.32	64.81	162.32

Company Insiders

Person / Entity	Transactions	Turnover, USD	Average, USD	First	Last
Lewis William	128	69,118,850.10	539,991.02	27/10/2023	18/08/2025
Flammer Martina M.d.	47	68,615,298.12	1,459,899.96	22/12/2023	02/09/2025
Schaeffer Orlov S Nicole	46	68,494,040.89	1,489,000.89	28/12/2023	12/09/2025
Bonstein Sara	38	48,131,573.78	1,266,620.36	22/12/2023	21/07/2025
Smith Michael Alexander	32	21,304,470.54	665,764.70	05/01/2024	02/09/2025
Adsett Roger	28	15,411,369.14	550,406.04	05/01/2024	19/08/2025
Sharoky Melvin Md	4	5,418,600.00	1,354,650.00	12/08/2025	12/09/2025
Wise John Drayton	12	2,730,939.95	227,578.33	03/01/2024	07/02/2025
Mcgirr David W J	4	903,070.00	225,767.50	03/06/2025	04/06/2025
Desjardins Clarissa	4	403,388.30	100,847.07	20/05/2025	21/05/2025

Insiders marked in yellow represent long-term insiders. These are individuals who have engaged in transactions for over 3 years and have conducted at least 10 transactions or reached a cumulative turnover of $1M USD. When examining transaction clusters, we prioritize those conducted by long-term insiders for analysis.

Connected Companies ³

Name	ISIN	Ticker
Rhythm Pharmaceuticals, Inc.	US76243J1051	RYTM

³ the firms where the current insiders have executed transactions.

Stock Advanced Metrics

Delta Correlation	subscribe 🔒
Upper Bound of Standardized Transaction Amount (ubsta), USD 4	subscribe 🔒

⁴ represents the maximum expected transaction amount for a company's insiders, calculated based on historical data. It provides insight into the typical range of insider transaction amounts and helps in identifying unusually large transactions.

⁵ a proprietary metric reflecting the consistency of insider trading behavior within a company. A higher discipline index suggests more regular and predictable insider transactions.