DENALI THERAPEUTICS INC.

DNLI US24823R1059

🆔
Registration No.
5414857
💰
Capitalization
Mid-cap

Denali Therapeutics Inc is a biotechnology company that is engaged in developing and discovering therapeutics to defeat neurodegeneration disease. The company's development programs include the LRRK2 Inhibitor Program, which develops brain penetrant small molecule LRRK2 inhibitor product candidates for Parkinson's disease. Its key products include DNL201, DNL151, DNL747, ATV (Antibody Transport Vehicle), ETV (Enzyme Transport Vehicle), and others.

🏢
Founded
2013
🔗
Website
https://www.denalitherapeutics.com
Annual Performance 1
2021 2022 2023 2024 2025
-37% -41% -22% -5% 2%
Annual Insiders Turnover, USD 2

1 annual and historical performance metrics are recalculated on a daily basis;
2 represents the total value of insider transactions (both buying and selling);

Insider Activity
📊
Transactions
61
🙍
Insiders
7
Person Price Shares Total Published Completed
Ho Carole
CMO 		14.64
USD 		806
Sold 		11,800
USD 		12/08/2025 13/08/2025
Ho Carole
CMO 		13.58
USD 		2,937
Sold 		39,884
USD 		12/08/2025 12/08/2025
Schuth Alexander O.
SEC 		13.58
USD 		2,937
Sold 		39,884
USD 		12/08/2025 12/08/2025
Watts Ryan J.
CEO 		15.00
USD 		495,282
Sold 		7,429,230
USD 		09/07/2025 09/07/2025
Schuth Alexander O.
SEC 		20.81
USD 		2,907
Sold 		60,495
USD 		06/01/2025 07/01/2025
Krognes Steve E.
O 		20.81
USD 		3,339
Sold 		69,485
USD 		07/01/2025 07/01/2025
Ho Carole
CMO 		20.81
USD 		2,907
Sold 		60,495
USD 		06/01/2025 07/01/2025
Watts Ryan J.
CEO 		20.81
USD 		7,650
Sold 		159,197
USD 		06/01/2025 07/01/2025
Schuth Alexander O.
SEC 		20.22
USD 		12,255
Sold 		247,796
USD 		06/01/2025 06/01/2025
Watts Ryan J.
CEO 		20.22
USD 		29,266
Sold 		591,759
USD 		06/01/2025 06/01/2025

Integrated EOD Stock Data and Insider Transactions Chart

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The visibility of insider buy and sell transactions on this chart should not be the sole factor in your decision to buy or sell a particular stock. Always consider the following dynamic reports for a broader understanding of stock market activities:

 

Historical Performance
1M 3M 6M 1Y 3Y 5Y All Time
-20% -13% 1% -27% -9% 0% -1%
Last 52W Low 52W High All-Time Low All-Time High β
14.90 11.47 31.58 11.47 93.56
Company Insiders
Person / Entity Transactions Turnover, USD Average, USD First Last
Watts Ryan J. 8 10,001,678.96 1,250,209.87 05/01/2024 09/07/2025
Krognes Steve E. 10 4,273,758.38 427,375.84 05/01/2024 07/01/2025
Schenkein David P 2 1,932,665.05 966,332.53 11/11/2024 11/11/2024
Schuth Alexander O. 13 1,662,044.98 127,849.61 05/01/2024 12/08/2025
Ho Carole 12 1,319,068.40 109,922.37 05/01/2024 13/08/2025
Sato Vicki L 15 584,410.26 38,960.68 15/11/2023 02/01/2025
Cook Jennifer E. 1 31,682.34 31,682.34 06/06/2024 06/06/2024

Insiders marked in yellow represent long-term insiders. These are individuals who have engaged in transactions for over 3 years and have conducted at least 10 transactions or reached a cumulative turnover of $1M USD. When examining transaction clusters, we prioritize those conducted by long-term insiders for analysis.

Stock Advanced Metrics
Delta Correlation subscribe 🔒
Upper Bound of Standardized Transaction Amount (ubsta), USD 4 subscribe 🔒

4 represents the maximum expected transaction amount for a company's insiders, calculated based on historical data. It provides insight into the typical range of insider transaction amounts and helps in identifying unusually large transactions.

5 a proprietary metric reflecting the consistency of insider trading behavior within a company. A higher discipline index suggests more regular and predictable insider transactions.